Plenhyage®, Nottingham

Regenerate. Repair. Rejuvenate.

Plenhyage® is an advanced bio-stimulator that repairs skin from within, improving tone, elasticity, and firmness for a naturally youthful glow.

The core of Plenhyage®’s efficacy lies in its use of Polynucleotides (PDRN), renowned for their remarkable wound-healing properties. These polymers play a pivotal role in repairing cellular damage and nourishing fibroblasts. They are critical in enhancing skin elasticity, hydration, and in repairing damage from sun exposure, photoaging, and various types of scarring, including acne-related scars.

The polynucleotide chain in Plenhyage® is distinguished by its ability to both attract water molecules and counteract free radicals. This dual functionality is crucial in neutralising OH hydroxyl radicals, which accumulate due to stress, cell damage, and environmental factors like UV exposure. Plenhyage® fosters anideal environment for fibroblast growth, rejuvenating tissue elasticity and promoting natural skin regeneration.

Key Benefits:
  • Deep Skin Regeneration – Stimulates fibroblast cells and collagen production
  • Improves Elasticity & Firmness – Visibly plumper, bouncier skin
  • Targets Fine Lines & Dullness – Revitalised, radiant skin tone
  • Reduces Inflammation & Redness – Soothes and strengthens the skin barrier
  • Safe for Delicate Areas – Ideal for under-eyes, neck, décolletage, and hands

What to expect with Plenhyage® at SLA™

Our approach to refreshing and repairing your skin

Step 01

Personalised Consultation

We analyse your skin type, concerns, and goals to ensure Plenhyage® is the right solution for you — and advise on complementary treatments if needed.

Step 02

Custom Treatment Plan

You’ll receive a bespoke treatment protocol (usually 2–3 sessions spaced 2–4 weeks apart), depending on the area and severity of concerns.

Step 03

Precision Treatment

Plenhyage® is precisely injected into the skin via fine needle or cannula. Treatment takes around 30 minutes and is generally well-tolerated.

Step 04
Aftercare & Results

Mild swelling or redness may occur for 24–48 hours. Over the following weeks, skin texture, tone, and hydration steadily improve — with optimal results seen after your full course.

Treatment Overview

Plenhyage® at Second Look Aesthetics

  • Consultation needed?: Yes
  • Treatment duration: 15-20 minutes
  • Is it painful? No
  • Time until fully healed: 2-3 weeks
  • Recovery/Downtime: 48hrs
  • Results last for:  6-12 months
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Our results speak for themselves

With over 2 decades of combined knowledge and experience, our highly trained aestheticians achieve incredible results for our clients, who travel from all over the world just to have their treatments done with us.

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Plenhyage® Pricing

£349
£349
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Frequently Asked Questions

About Plenhyage® at our Clinic in Nottingham

Is Plenhyage® suitable for me?

Plenhyage is ideal for individuals looking to improve skin quality, texture, and hydration. It’s especially beneficial for dull, tired or ageing skin and can be used on the face, neck, or hands. At Second Look Aesthetics, we recommend it for clients seeking bio-stimulation without added volume.

What can I expect from Plenhyage®?

Plenhyage promotes collagen production and skin regeneration, leaving your skin smoother, brighter, and more hydrated. Results develop over time with a course of treatments. There’s little to no downtime, though mild redness may occur.

What products are used for Plenhyage®?

At Second Look Aesthetics, we use the product Venufill for all non-surgical BBL in Nottingham, East Midlands. We are also able to administer the treatment using Hyacorp if preferred, which will be at an additional cost.

How much product is needed for Plenhyage® treatments?

Plenhyage® is one of our most effective treatments available. We generally suggest a minimum of two sessions to achieve optimal results and ensure long-lasting effects. As this treatment is regenerative, it will continue to work powerfully after the first two weeks, intensifying cell regeneration. Typically, each session utilises 2ml of product, depending on the treatment area. For instance, 2ml usually covers the entire face, including the malar and sub-malar regions, or it can be focused on specific areas like the jawline. For the neck, 2ml is required. The under-eye area also requires 2ml, meaning if you're treating the face or neck as well, additional product will be necessary. Clients generally require 2ml per area, although this amount may vary based on the size and condition of the targeted area.

How long does Plenhyage® take in Nottingham?

Your appointment will usually last around 15 to 20 minutes, including consultation, assessment, and treatment. It’s a quick and efficient procedure that easily fits into your day.

How long do the results of Plenhyage® last?

After completing both initial sessions, results typically last between 6 to 12 months, depending on your skin type and lifestyle choices. Following this, we usually recommend a touch-up every 4 to 6 months to maintain the benefits. This treatment is highly potent, and one of its most remarkable features is that it continues to work actively within the body long after application, promoting long-term skin regeneration and vitality.

Are there any side effects to Plenhyage® Treatments?

Plenhyage® is generally well tolerated and considered low risk. As with any injectable, you might experience slight redness, swelling, or tenderness at the injection site, which usually resolves within 24 to 48 hours. Bruising is uncommon but can occasionally happen.

Is Plenhyage® painful?

Discomfort is minimal. A topical numbing cream may be applied beforehand to ensure comfort during the procedure. Most clients describe the sensation as a mild pinch or pressure, and it is generally very well tolerated.

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